{"id":8494,"date":"2022-02-08T23:43:25","date_gmt":"2022-02-08T15:43:25","guid":{"rendered":"https:\/\/www.cytologics.com.hk\/?p=8494"},"modified":"2024-05-18T10:24:43","modified_gmt":"2024-05-18T02:24:43","slug":"nmn-%e4%bd%bf%e9%aa%a8%e7%b5%84%e7%b9%94%e5%b9%b9%e7%b4%b0%e8%83%9e%e6%81%a2%e5%be%a9%e6%b4%bb%e5%8a%9b","status":"publish","type":"post","link":"https:\/\/cytologics.com\/tc\/nmn-%e4%bd%bf%e9%aa%a8%e7%b5%84%e7%b9%94%e5%b9%b9%e7%b4%b0%e8%83%9e%e6%81%a2%e5%be%a9%e6%b4%bb%e5%8a%9b\/","title":{"rendered":"NMN \u80fd\u4f7f\u9aa8\u7d44\u7e54\u5e79\u7d30\u80de\u6062\u5fa9\u6d3b\u529b"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"8494\" class=\"elementor elementor-8494\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"gap-default elementor-section elementor-top-section elementor-element elementor-element-effd3cb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"effd3cb\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a04cfa6\" data-id=\"a04cfa6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aee60f5 elementor-widget elementor-widget-text-editor\" data-id=\"aee60f5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h1>\u8a66\u5291\u7159\u9170\u80fa\u55ae\u6838\u82f7\u9178 (NMN) \u8207\u6838\u5c0f\u9ad4\u7d44\u88dd\u86cb\u767d 1 like-2 (NAP1L2) \u5c0d\u63a5\uff0c\u4ee5\u91cd\u632f\u9aa8\u9593\u5145\u8cea\u5e79\u7d30\u80de\u7684\u201c\u5e79\u7d30\u80de\u7279\u6027\u201d\u3002<\/h1>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b217658 elementor-widget elementor-widget-text-editor\" data-id=\"b217658\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>By Brett J. Weiss<\/p><p>Published: 2:52 p.m. PST Feb 8, 2022 | Updated: 6:18 p.m. PST Feb 8, 2022<\/p><p>\u00a0<\/p><h3>\u91cd\u5927\u4eae\u9ede<\/h3><p>\u00a0<\/p><div>\u2022\u8a72\u7814\u7a76\u8868\u660e\uff0cNMN\u8207SIRT1\u86cb\u767d\u7d50\u5408\uff0c\u6fc0\u6d3b\u9aa8\u9abc\u518d\u751f\uff08\u6210\u9aa8\uff09\u7684\u57fa\u56e0\u3002<\/div><div>\u2022\u901a\u904e\u523a\u6fc0\u6210\u9aa8\u4f5c\u7528\uff0cNMN\u53ef\u9632\u6b62\u9aa8\u8cea\u758f\u9b06\u75c7\u7684\u767c\u5c55\u3002<\/div><p>\u00a0<\/p><p>\u96a8\u8457\u4eba\u5011\u5e74\u9f61\u7684\u589e\u9577\uff0c\u65b0\u9aa8\u7d30\u80de\u7684\u5206\u89e3\u548c\u751f\u6210\uff08\u6210\u9aa8\uff09\u4e5f\u5728\u4e0b\u964d\u3002\u9aa8\u9abc\u518d\u751f\u7684\u6df7\u4e82\u6e90\u65bc\u5e79\u7d30\u80de\u5728\u5176\u539f\u59cb\u7684\u3001\u5e74\u8f15\u7684\u72c0\u614b\uff08\u5e79\u7d30\u80de\u7279\u6027\uff09\u4e2d\u88ab\u8017\u76e1\u3002\u9aa8\u5e79\u7d30\u80de\u7684\u5e79\u7d30\u80de\u7279\u6027\u4e0b\u964d\u662f\u7531\u65bc\u5e79\u7d30\u80de\u5728\u901a\u904e\u7d30\u80de\u9031\u671f\u9032\u5c55\u5230\u6210\u719f\u70ba\u6210\u9aa8\u7d30\u80de\u6642\u7684\u7a81\u8b8a\u7a4d\u7d2f\u3002<\/p><p>\u63db\u53e5\u8a71\u8aaa\uff0c\u7576\u5e79\u7d30\u80de\u8b8a\u6210\u6210\u9aa8\u7d30\u80de\u6642\uff0c\u9aa8\u9abc\u6703\u8b8a\u786c\uff0c\u53ef\u80fd\u5bb9\u6613\u9aa8\u6298\uff0c\u4e26\u51fa\u73fe\u5b54\u9699\uff08\u9aa8\u8cea\u758f\u9b06\u75c7\uff09\uff0c\u5c0e\u81f4\u865b\u5f31\u3002\u81e8\u5e8a\u91ab\u751f\u53ef\u4ee5\u7528\u865b\u5f31\u6307\u6578\u4f86\u8861\u91cf\u865b\u5f31\u7a0b\u5ea6\uff0c\u9019\u500b\u6578\u5b57\u4ee3\u8868\u4e86\u8001\u5e74\u4eba\u7684\u6574\u9ad4\u9ad4\u80fd\u548c\u5065\u5eb7\u72c0\u6cc1\u3002\u7531\u65bc\u9019\u4e9b\u539f\u56e0\uff0c\u7814\u7a76\u7684\u65b9\u5411\u662f\u5c0b\u627e\u7dad\u6301\u9aa8\u9593\u8cea\u5e79\u7d30\u80de\uff08BMSCs\uff09\u7684\u5e79\u7d30\u80de\u7279\u6027\u7684\u65b9\u6cd5\uff0c\u9aa8\u9593\u8cea\u5e79\u7d30\u80de\u662f\u7522\u751f\u6210\u9aa8\u7d30\u80de\u7684\u5e79\u7d30\u80de\uff0c\u540c\u6642\u4e5f\u662f\u9aa8\u7d44\u7e54\u7684\u5e79\u7d30\u80de\u3002<\/p><p>\u00a0<\/p><h3>NMN \u5728\u57fa\u56e0\u4e0a\u7ffb\u65b0\u8001\u5e74\u4eba\u7684\u9aa8\u5e79\u7d30\u80de<\/h3><p>\u00a0<\/p><p>\u5148\u524d\u7684\u7814\u7a76\u8868\u660e\uff0c\u7159\u9170\u80fa\u817a\u560c\u5464\u4e8c\u6838\u82f7\u9178 (NAD+) \u7684\u76f4\u63a5\u524d\u9ad4\u7159\u9170\u80fa\u55ae\u6838\u82f7\u9178 (NMN) \u53ef\u4ee5\u6062\u5fa9\u8001\u9f20\u548c\u5927\u9f20\u7b49\u56d3\u9f52\u52d5\u7269\u7684\u9aa8\u7d44\u7e54\u5065\u5eb7\u3002 \u8a71\u96d6\u5982\u6b64\uff0c\u5929\u6d25\u91ab\u79d1\u5927\u5b78\u7684Liu\u548c\u540c\u4e8b\u5229\u7528\u5e74\u8f15\u548c\u8001\u5e74\u60a3\u8005\u7684\u9aa8\u9ad3\u9593\u5145\u8cea\u4e7e\u7d30\u80de\u4f86\u6e2c\u8a66\u65bd\u7528 NMN \u662f\u5426\u80fd\u6062\u5fa9\u9019\u4e9b\u7d30\u80de\u4e2d\u7684\u8868\u89c0\u907a\u50b3\u5bc6\u78bc\uff0c\u5373\u57fa\u56e0\u8868\u9054\u7684\u5e74\u8f15\u6a21\u5f0f\u3002 \u5728\u6b64\u904e\u7a0b\u4e2d\uff0c\u4f4d\u65bc\u5929\u6d25\u7684\u7814\u7a76\u5c0f\u7d44\u767c\u73fe\uff0c\u63a5\u53d7\u5316\u7642\u548c\u6c27\u5316\u61c9\u6fc0\u7684 BMSC \u5728\u63a5\u53d7 NMN \u6cbb\u7642\u5f8c\u8868\u73fe\u51fa\u589e\u5f37\u7684\u5e79\u7d30\u80de\u7279\u6027\u3002 \u6709\u8da3\u7684\u662f\uff0c\u4e2d\u570b\u5718\u968a\u5831\u544a\u4e86\u9032\u4e00\u6b65\u7684\u6578\u64da\uff0c\u986f\u793a NMN \u8207 DNA \u7d50\u5408\uff0c\u53ef\u80fd\u4f7f\u57fa\u56e0\u8868\u9054\u8b5c\u6062\u5fa9\u6d3b\u529b\u3002<\/p><p>\u00a0<\/p><p>\u86cb\u767d\u8cea\u6838\u5c0f\u9ad4\u7d44\u88dd\u86cb\u767d 1-like 2 (NAP1L2) \u7684\u8868\u9054\u589e\u52a0\u8207\u8870\u8001\u76f8\u95dc\u3002 Liu \u53ca\u5176\u540c\u4e8b\u5047\u8a2d\uff0c\u96a8\u8457 NAP1L2 \u6c34\u5e73\u7684\u589e\u52a0\uff0c\u9019\u7a2e\u86cb\u767d\u8cea\uff08\u4e00\u7a2e\u6838\u5c0f\u9ad4\u4f34\u4fb6\uff09\u6703\u5f9e DNA \u5305\u88f9\u7684\u86cb\u767d\u8cea\uff08\u6838\u5c0f\u9ad4\uff09\u4e2d\u53bb\u9664\u7a31\u70ba\u4e59\u9170\u57fa\u7684\u5206\u5b50\u6a19\u7c64\u3002 NAP1L2 \u9084\u62db\u52df\u53bb\u4e59\u9170\u5316\u9176\u86cb\u767d Sirtuin1 (SIRT1)\uff0c\u8a72\u86cb\u767d\u5f9e\u9a45\u52d5\u6210\u9aa8\u7684\u57fa\u56e0\u7684\u555f\u52d5\u5b50\u5340\u57df\u53bb\u9664\u4e59\u9170\u57fa\u5718\u3002<\/p><p>\u00a0<\/p><h3>NAP1L2 \u86cb\u767d\u8cea\u6c34\u5e73\u96a8\u8457\u5e74\u9f61\u7684\u589e\u9577\u800c\u589e\u52a0\uff0c\u8207\u8eab\u9ad4\u865b\u5f31\u76f8\u95dc<\/h3><p>\u00a0<\/p><p>\u70ba\u4e86\u9a57\u8b49\u9019\u4e00\u60f3\u6cd5\uff0c\u4f4d\u65bc\u5929\u6d25\u7684\u7814\u7a76\u5c0f\u7d44\u8a66\u5716\u5c07NAP1L2\u86cb\u767d\u8868\u9054\u7684\u589e\u52a0\u8207\u8001\u5e74\u4eba\u7684BMSCs\u4e2d\u7684\u8870\u8001\u806f\u7e6b\u8d77\u4f86\u3002\u70ba\u4e86\u6e2c\u91cf\u8870\u8001\uff0c\u7814\u7a76\u4eba\u54e1\u7528\u5206\u5b50\u6a19\u8a18\u7269\u03b2-\u534a\u4e73\u7cd6\u82f7\u9176\u6e2c\u91cf\u8870\u8001\u3002\u4ed6\u5011\u9084\u767c\u73fe\u4e86\u67d3\u8272\u9ad4\u672b\u7aef\uff08\u7aef\u7c92\uff09\u7684\u529f\u80fd\u969c\u7919\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0c\u4ed6\u5011\u5c0d\u8001\u5e74BMSC\u86cb\u767d\u6c34\u5e73\u7684\u5206\u6790\u767c\u73fe\uff0c\u5728\u7528\u904e\u6c27\u5316\u6c2b\uff08H2O2\uff09\u5c0dBMSCs\u65bd\u52a0\u58d3\u529b\u5f8c\uff0c\u8870\u8001\u76f8\u95dc\u7684\u5206\u6ccc\u8868\u578b\uff08SASP\uff09\u6a19\u8a8c\u7269\u8207NAP1L2\u6c34\u5e73\u7684\u589e\u52a0\u540c\u6b65\u3002\u9019\u4e9b\u7d50\u679c\u8868\u660e\uff0cBMSC\u7684\u8870\u8001\u548c\u5e79\u7d30\u80de\u7279\u6027\u55aa\u5931\u8207NAP1L2\u6c34\u5e73\u7684\u5347\u9ad8\u540c\u6b65\u767c\u751f\u3002<\/p><h3>\u00a0<\/h3><h3>NMN \u8207 NAP1L2 \u7d50\u5408\u4ee5\u523a\u6fc0\u7d30\u80de\u518d\u751f SIRT1 \u86cb\u767d<\/h3><p>\u00a0<\/p><p>\u70ba\u4e86\u4e86\u89e3 NMN \u662f\u5982\u4f55\u5f71\u97ff\u8001\u5e74\u4eba BMSCs \u4e2d\u7684 NAP1L2 \u6c34\u5e73\u7684\uff0cLiu \u53ca\u5176\u540c\u4e8b\u5728\u5be6\u9a57\u5ba4\u57f9\u990a\u76bf\u4e2d\u7528 1 mM NMN \u6fc3\u5ea6\u4ecb\u5165\u4e86 BMSCs\u3002 \u7814\u7a76\u5c0f\u7d44\u767c\u73fe\uff0c\u6709\u8da3\u7684\u662f\uff0cNMN \u8207 NAP1L2 \u86cb\u767d\u5c0d\u63a5\uff0c\u4e26\u4e14\u9084\u6e1b\u8f15\u4e86\u8207\u8870\u8001\u76f8\u95dc\u7684 \u03b2-\u534a\u4e73\u7cd6\u82f7\u9176\u7684\u7a4d\u7d2f\u3002 \u4e0d\u50c5\u5982\u6b64\uff0cNMN \u6cbb\u7642\u9084\u6e1b\u8f15\u4e86\u8870\u8001 BMSCs \u4e2d\u7aef\u7c92 DNA \u640d\u50b7\u7684\u7a4d\u7d2f\u3002 \u6b64\u5916\uff0c\u7528 NMN \u4ecb\u5165\u7d30\u80de\u9084\u6291\u5236\u4e86 SASP \u56e0\u5b50\u57fa\u56e0\u7684\u8868\u9054\u3002 \u9019\u4e9b\u7d50\u679c\u8868\u660e\uff0c\u81f3\u5c11\u5728\u5be6\u9a57\u5ba4\u57f9\u990a\u76bf\u4e2d\uff0cNMN \u53ef\u4ee5\u4f7f BMSCs \u6062\u5fa9\u6d3b\u529b\u3002 \u5982\u679c\u9019\u4e9b\u767c\u73fe\u5728\u6d3b\u4eba\u4e2d\u5177\u6709\u91cd\u8981\u610f\u7fa9\uff0c\u5247\u53ef\u80fd\u610f\u5473\u8457\u4f7f\u7528 NMN \u53ef\u4ee5\u6062\u5fa9 BMSC \u7684\u201c\u5e79\u7d30\u80de\u7279\u6027\u201d\uff0c\u53ef\u80fd\u6703\u6062\u5fa9\u6210\u9aa8\u529f\u80fd\uff0c\u7de9\u89e3\u4eba\u985e\u8870\u8001\u5f8c\u7684\u9aa8\u8cea\u758f\u9b06\u75c7\u3002<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-264e4f6 elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"264e4f6\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img fetchpriority=\"high\" decoding=\"async\" width=\"895\" height=\"419\" src=\"https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/814909_988505.jpeg\" class=\"attachment-full size-full wp-image-8497\" alt=\"NMN Eto\" \/><\/figure><div class=\"elementor-image-box-content\"><p class=\"elementor-image-box-description\">(Liu et al. 2022 | Aging Cell) NMN \u53ef\u9632\u6b62\u9aa8\u7d30\u80de\u8870\u8001\u7684\u7a4d\u7d2f\u3002 \u7d50\u5408 NAP1L2 \u7684\u5316\u5408\u7269\u7684\u8a08\u7b97\u6a5f\u5efa\u6a21\u53ef\u8b58\u5225 NMN\uff08\u5de6\uff09\u3002 \u7d66\u4e88\u5316\u7642\u5291\u4f9d\u6258\u6cca\u82f7\uff08Eto\uff0948\u5c0f\u6642\u4ee5\u8a98\u5c0e\u7d30\u80de\u8870\u8001\u3002 \u4e8b\u5be6\u4e0a\uff0c\u5927\u7d04 80% \u7684\u9aa8\u9ad3\u5e79\u7d30\u80de (BMSCs) \u8b8a\u5f97\u8870\u8001\u3002 \u5728\u9019 48 \u5c0f\u6642\u5167\u7528 NMN \u8655\u7406\u76f8\u540c\u7684\u7d30\u80de\u53ef\u4f7f\u8870\u8001\u7d30\u80de\u7684\u767e\u5206\u6bd4\u964d\u4f4e\u7d04 50%\uff08\u53f3\u5716\uff09\u3002\n<\/p><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d797f13 elementor-widget elementor-widget-text-editor\" data-id=\"d797f13\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u8b49\u5be6\u9019\u4e00\u6982\u5ff5\u7684\u9032\u4e00\u6b65\u8b49\u64da\u4f86\u81ea\u4e00\u9805\u4eba\u9ad4\u81e8\u5e8a\u8a66\u9a57\uff0c\u8868\u660e NAP1L2 \u6c34\u5e73\u5347\u9ad8\u8207\u8001\u5e74\u4eba\u7684\u9aa8\u8cea\u758f\u9b06\u75c7\u76f8\u95dc\u3002 \u4f8b\u5982\uff0c\u767c\u73fe NAP1L2 \u8868\u9054\u8207\u9aa8\u5bc6\u5ea6\u4e4b\u9593\u5b58\u5728\u8ca0\u76f8\u95dc\uff0c\u9019\u610f\u5473\u8457\u96a8\u8457\u5e74\u9f61\u7684\u589e\u9577\u548c NAP1L2 \u6c34\u5e73\u7684\u589e\u52a0\uff0c\u9aa8\u9abc\u8b8a\u5f97\u66f4\u52a0\u591a\u5b54\u3002 \u5118\u7ba1\u9700\u8981\u9032\u4e00\u6b65\u6e2c\u8a66\uff0c\u4f46\u88dc\u5145 NMN \u53ef\u4ee5\u589e\u52a0\u4eba\u9ad4\u9aa8\u5bc6\u5ea6\u4ee5\u4f7f\u9aa8\u9abc\u66f4\u5f37\u58ef\u7684\u53ef\u80fd\u6027\u4ecd\u7136\u5b58\u5728\u3002 NMN \u8a66\u5291\u7684\u524d\u666f\u610f\u5473\u8457\u4eba\u985e\u53ef\u4ee5\u5f9e\u88dc\u5145\u8a72\u5316\u5408\u7269\u4e2d\u53d7\u76ca\uff0c\u96a8\u8457\u5e74\u9f61\u7684\u589e\u9577\uff0c\u53ef\u80fd\u6703\u9006\u8f49\u865b\u5f31\u6307\u6578\u5f97\u5206\u3002 \u9019\u6a23\u505a\uff0c\u6211\u5011\u53ef\u4ee5\u904e\u4e0a\u66f4\u5065\u5eb7\u7684\u751f\u6d3b\uff0c\u4e26\u6709\u671b\u6e1b\u8f15\u8001\u5e74\u4eba\u7684\u60b2\u50b7\u548c\u7d55\u671b\u3002 \u4e5f\u8a31\u901a\u904e\u6539\u5584\u6574\u9ad4\u5e78\u798f\u611f\uff0c\u670d\u7528 NMN \u7684\u8001\u5e74\u4eba\u53ef\u4ee5\u6709\u66f4\u597d\u7684\u4eba\u751f\u89c0\uff0c\u63d0\u4f9b\u6f5b\u5728\u7684\u6a02\u89c0\u4f86\u6e90\u3002<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3003dd1 elementor-widget elementor-widget-text-editor\" data-id=\"3003dd1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u53c3\u8003\u6587\u737b:<\/p><p>\u00a0<\/p><p>Hu M, Xing L, Zhang L, Liu F, Wang S, Xie Y, Wang J, Jiang H, Guo J, Li X, Wang J, Sui L, Li C, Liu D, Liu Z. NAP1L2 drives mesenchymal stem cell senescence and suppresses osteogenic differentiation. Aging Cell. 2022 Jan 15:e13551. doi: 10.1111\/acel.13551. Epub ahead of print. PMID: 35032339<\/p><p>\u00a0<\/p><p>\u6587\u7ae0\u4f86\u6e90:<\/p><p>\u00a0<\/p><p>https:\/\/www.nmn.com\/news\/nmn-restores-stem-cells-bone-tissue-activating-nap1l2-protein<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u8a66\u5291\u7159\u9170\u80fa\u55ae\u6838\u82f7\u9178 (NMN) \u8207\u6838\u5c0f\u9ad4\u7d44\u88dd\u86cb\u767d 1 like-2 (NAP1L2) \u5c0d\u63a5\uff0c\u4ee5\u91cd\u632f\u9aa8\u9593\u5145\u8cea\u5e79\u7d30&#8230;<\/p>\n","protected":false},"author":1,"featured_media":8501,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[180],"tags":[],"class_list":["post-8494","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-180","nt-post-class","","excerpt-none"],"acf":[],"publishpress_future_action":{"enabled":false,"date":"2026-08-02 15:16:27","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"rttpg_featured_image_url":{"full":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"landscape":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"portraits":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"thumbnail":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022-150x150.jpg",150,150,true],"medium":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022-300x183.jpg",300,183,true],"large":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"1536x1536":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"2048x2048":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false],"trp-custom-language-flag":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022-18x12.jpg",18,12,true],"goldsmith-quickview":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",60,37,false],"goldsmith-panel":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",80,49,false],"goldsmith-mini":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",300,183,false],"goldsmith-medium":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",370,226,false],"goldsmith-square":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",500,306,false],"goldsmith-grid":["https:\/\/cytologics.com\/wp-content\/uploads\/2022\/02\/327587_344022.jpg",677,414,false]},"rttpg_author":{"display_name":"nkcomys","author_link":"https:\/\/cytologics.com\/tc\/author\/nkcomys\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/cytologics.com\/tc\/%e7%a7%91%e7%a0%94%e8%b3%87%e8%a8%8a\/\" rel=\"category tag\">\u79d1\u7814\u8cc7\u8a0a<\/a>","rttpg_excerpt":"\u8a66\u5291\u7159\u9170\u80fa\u55ae\u6838\u82f7\u9178 (NMN) \u8207\u6838\u5c0f\u9ad4\u7d44\u88dd\u86cb\u767d 1 like-2 (NAP1L2) \u5c0d\u63a5\uff0c\u4ee5\u91cd\u632f\u9aa8\u9593\u5145\u8cea\u5e79\u7d30...","_links":{"self":[{"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/posts\/8494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/comments?post=8494"}],"version-history":[{"count":20,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/posts\/8494\/revisions"}],"predecessor-version":[{"id":17264,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/posts\/8494\/revisions\/17264"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/media\/8501"}],"wp:attachment":[{"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/media?parent=8494"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/categories?post=8494"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cytologics.com\/tc\/wp-json\/wp\/v2\/tags?post=8494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}